Amy Schumer took to motherhood like a duck to water when she welcomed son Gene in May 2019. However her journey to motherhood was not ideal.

Hyperemesis gravidarum and endometriosis caused a lot of suffering for the Trainwreck star, and now she has revealed just how difficult her IVF journey was.

In a recent episode of Chelsea Handler’s podcast, Dear Chelsea, Amy Schumer said she had a difficult time with IVF when she and her husband, Chris Fischer, tried to conceive their second child.

“I did IVF, we made embryos and I went through the IVF process, which is so hard. People do it so many times. I did it one time and I was like, I’m gonna die. This is awful,” she said on the podcast.

Amy said while they retrieved 31 eggs during the process, they were left with one embryo, which unfortunately didn’t take.

Last year, Amy underwent surgery to remove her uterus and appendix due to severe endometriosis. Which means she can no longer carry a baby of her own.

“So we’re gonna have just one child and we’re just enjoying our little family and I’m just focusing on that,” said the I Feel Pretty star.

“I’m excited about it but I was sad. And it’s not really something you get sympathy for because it’s like, you already have one b*tch, shut up. But you know, that’s a real struggle people go through.”

“We tried, but yeah we’re just gonna have the one perfect little adorable angel.”

The couple have been open about their fertility struggles, in August last year during an interview on Sunday Today with Willie Geist, the mum-of-one admits: “We did IVF and IVF was really tough on me,” adding: “I don’t think I could ever do IVF again.”

“I don’t think I could ever do IVF again.”

In January 2021, the I feel Pretty star shared a confronting image that shows her bruised abdomen and C-section scar on Instagram, sharing that she was one week into IVF treatment to save her eggs.

“I’m a week into IVF and feeling really run down and emotional,” confessed the Snatched star.

“If anyone went through it and if you have any advice or wouldn’t mind sharing your experience with me please do.”

At the time the comedian admitted that she and husband Chris Fischer had not quite decided when or how it will be that Gene will become a big brother.

“We are freezing my eggs and figuring out what to do to give Gene a sibling,” she penned.

Always one to keep things real, Amy Schumer’s IVF experience has been an open book from the very beginning.

Debilitating hyperemesis gravidarum meant that Amy’s first pregnancy was not ideal.

Hyperemesis gravidarum is an extreme version of morning sickness, and in Amy’s case she suffered it terribly throughout her entire pregnancy.

Daily bouts of vomiting were so bad for the star that they often left her bedridden and dehydrated, and at times saw her hospitalised.

Amy’s long-term battle with endometriosis also proved problematic for surgeons during her caesarean section adding to the speculation that childbirth might not be a viable option for the star again.

Debilitating hyperemesis gravidarum meant that Amy’s first pregnancy was not ideal.

The comedian, who openly shared her pregnancy battle with hyperemesis gravidarum via social media with fans has been honest from the very beginning about the pretty and not-so-pretty aspects of motherhood.

Speaking on Dr. Berlin’s Informed Pregnancy podcast, Amy shared: “I was throwing up through the whole first hour of my C-section. It’s supposed to take about an hour and a half or something but mine took over three hours because of my endometriosis.”

The Trainwreck star also spoke of her breastfeeding reality on the podcast, admitting that it just wasn’t for her.

“I wanted him to get the colostrum,” she said.

“We had a lactation expert come over. He didn’t latch and I just didn’t feel that push to make that happen. Then I pumped for like the first month. Then I was like, ‘Not for me.’ This is not for me and I didn’t want to do it.”

With so much pressure on new mums to breastfeed, Amy normalised that it might not be for everyone by confessing: “Some people just absolutely love it and I’m so happy for them, and it was just bumming me out.

“But then I was also kind of proud doing it and whatever and getting him the milk and stuff. Then once it occurred to me that I could stop. I was like, ‘I’m going to stop’ … And then, every week what I did was just took away one session of the pumping.”

WATCH: Amy Schumer is hilarious in her last week of pregnancy